If you have a look at the product availability guide you will find out, depending on the version of Windows 7 you are using, which OpenEdge version is supported on it. AFAIK no plain 10.1B is supported on any Windows 7. Therefore, it might work on some machines, whereas it won't work on others - YMMV. Only if the installations of Windows 7 on your PC and on the PC you use at work would be identical, it should run on both of the machines or on none.
Heavy Regards, RealHeavyDude.